In tissue that is ischemic, vasodilation can be induced to enhance the effects of radiotherapy by increasing the delivery of oxygen and blood to the target. Vasodilation can also aid drug treatments by increasing the amount of the drug delivered to a target.
Focused ultrasound can create a pressure change at a precise location, triggering the endothelium of targeted blood vessels to release nitric oxide, the chemical signal that causes smooth muscle relaxation and the dilation of blood vessels 1. This is a reversible process, and blood vessels revert to their original size shortly after the end of the focused ultrasound treatment with no permanent damage to targeted tissue 1,2.
Thermal effects are minimal when pulsed focused ultrasound is used, however, local hyperthermia will also cause localized vasodilation. Certain drugs have been shown to more easily diffuse across dilated vessels, increasing the bioavailability of these drugs in surrounding tissues. Furthermore, dilated blood vessels carry a larger volume of blood, potentially providing a further increase in the amount of drugs absorbed by tissue 3.
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Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. For details see our conditions. In this article What are peripheral vasodilators? When are peripheral vasodilators usually prescribed? How do peripheral vasodilators work? Which peripheral vasodilator is usually prescribed?
How should I take peripheral vasodilators? What are the possible side-effects? Other considerations Can I buy peripheral vasodilators? Who cannot take peripheral vasodilators? Peripheral Vasodilators In this article What are peripheral vasodilators? What are peripheral vasodilators? How to use the Yellow Card Scheme If you think you have had a side-effect to one of your medicines you can report this on the Yellow Card Scheme.
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This makes them less able to constrict and dilate as needed. The air at high altitudes contains less available oxygen. A person at high altitude will therefore experience vasodilation as their body attempts to maintain oxygen supply to its cells and tissues. Although vasodilation decreases blood pressure in major blood vessels, it can increase blood pressure in smaller blood vessels called capillaries.
This is because capillaries do not dilate in response to increased blood flow. Increased blood pressure within the capillaries of the brain can cause fluid to leak into surrounding brain tissue. This results in localized swelling, or edema. Medical professionals refer to this condition as high-altitude cerebral edema HACE. People at high altitudes may also experience vasoconstriction within the lungs. This can cause a buildup of fluid within the lungs, which medical professionals refer to as high-altitude pulmonary edema HAPE.
In some cases, a doctor may induce vasodilation as a treatment for certain conditions. In other cases, vasodilation may be what requires treatment. Vasodilators are medications that cause the blood vessels to widen. Doctors may use these drugs to reduce blood pressure and ease any strain on the heart muscle. There are two types of vasodilator: drugs that work directly on the smooth muscle, such as that in the blood vessels and heart, and drugs that stimulate the nervous system to trigger vasodilation.
The type of vasodilator a person receives will depend on the condition they have that needs treatment. Vasodilation is an important mechanism. However, it can sometimes be problematic for people who experience hypotension or chronic inflammation. People with either of these conditions may require medications called vasoconstrictors.
These drugs cause the blood vessels to narrow. For people with hypotension, vasoconstrictors help increase blood pressure. For people with chronic inflammatory conditions, vasoconstrictors reduce inflammation by restricting blood flow to certain cells and body tissues. Vasodilation refers to the widening, or dilation, of the blood vessels. It is a natural process that increases blood flow and provides extra oxygen to the tissues that need it most.
Vasodilators are medications that open dilate blood vessels. They affect the muscles in the walls of the arteries and veins, preventing the muscles from tightening and the walls from narrowing. As a result, blood flows more easily through the vessels.
The heart doesn't have to pump as hard, reducing blood pressure. Some drugs used to treat hypertension, such as calcium channel blockers also dilate blood vessels. But the vasodilators that work directly on the vessel walls are hydralazine and minoxidil. Doctors prescribe vasodilators to prevent, treat or improve symptoms in a variety of conditions, such as:. Direct vasodilators are strong medications that generally are used only when other medications haven't controlled blood pressure adequately.
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